What is the Best Form of Vitamin B12 for Supplement Products?

what is the best form of vitamin b12 supplement

When you are vegan, supplementing is sometimes necessary to ensure you are getting all of the nutrients you need to be healthy. 

Getting the best form of vitamin b12 in your supplements is just as important. 

While you can ideally get all of the nutrition you need directly from your food, sometimes you need a little assistance in the form of supplements. 

One of the most common supplements that vegans take is vitamin B12. This vitamin is essential for your overall health and plays a massive role in your body’s basic functions. 

Like most vitamins, there are multiple different forms of vitamin B12, all slightly different in their own ways. 

Let’s explore the best forms of vitamin B12 for use in supplements to ensure you are getting the best results out of your product choices.

Why is Vitamin B12 So Important?

Vitamin B12 is a nutrient that plays a crucial role in many of your body’s basic functions. It is most known for keeping your nerve and blood cells healthy while supporting DNA formation. 

DNA is the basis of what makes your cells work and able to replicate and contains all of your genetic information, so this is incredibly important. 

Additionally, the best form of vitamin B12 also helps to prevent anemia and keep your body’s blood circulating as it should.

Knowing this, it probably makes sense why getting enough of this nutrient is so important.

So, What Is the Best Form of Vitamin B12?

There are numerous different types of vitamin B12, all with different purposes and impacts on the body. 

Of all of these, there are two that really seem to have the biggest beneficial input on the overall health and functionality of the human body. 

These are methylcobalamin and adenosylcobalamin.


Methylcobalamin is the most easily absorbed form of vitamin B12 that you will see most commonly included in supplements. 

This is because our bodies readily accept this form of the nutrient without requiring any additional ingredients. 

Due to this, it is used more effectively by the liver, brain, and nervous system while also helping to prevent diabetes and heart disease by helping in the metabolism of a protein known as homocysteine, which has known inflammatory properties if left unmetabolized in the body. 

Methylcobalamin is also linked with enhancing mental clarity and thought processing due to its ability to help clear brain fog and support mental health. 

Let’s look at a couple of methylcobalamin-based supplements.

At 5,000 mcg, this product delivers a definitive punch of methylcobalamin B12. 

With its energy-supporting and metabolism-boosting formula, this Solgar product works in your favor by providing a boost of vitamin B12 in a vegan, easy to absorb formulation. 

This product is also free of gluten, wheat, dairy, soy, yeast, sugar, sodium, artificial flavor, sweetener, and color, and made to the standard of this 70-year-old, high-quality company’s expectations. 

This sublingual product dissolves in the mouth and is easily absorbed directly into the bloodstream, providing faster results, too.

This vegetable-based gel cap from Doctor’s Best is fully active and easy to absorb. 

Delivering an ortho-molecule that is identical to the readily available form within the human body, this is one of the forms that will most easily mesh after supplement digestion. 

Designed to support mood, memory, circulation, and wellbeing, this affordable product is perfect for those looking to test out vitamin B12 supplementation for the first time due to its cost-effective but impactful nature.


Also known as dibencozide, adenosylcobalamin is another form of B12 that is easy to absorb and works well with the human body. 

This form has the added benefit of also being extra-suitable for athletes since it works as a support system for energy production during the Kreb cycle for ATP production. 

It also supports branched-chain amino acid metabolism and usage, too. 

There are products that use adenosylcobalamin readily available online, though most are a blend of adenosylcobalamin and methylcobalamin.

If you are looking for a sublingual spray formula that goes directly into the bloodstream while containing adequate amounts of methylcobalamin, adenosylcobalamin, and other forms of vitamin B12 like hydroxocobalamin, this product might be worth checking out. 

As a full spectrum spray, it features the three most common types of vitamin B12 all at once, branching the entire spectrum of vitamin B12 types. 

Designed by Ideal Fusion, this product comes in two flavors: cinnaplum and boysenberry, both of which are pleasant and make holding the sublingual comfortable and easy, making this product suitable for those who prefer a lighter experience without sacrificing dosage.

These sublingual drops also use all three forms of commonly marketed vitamin B12. 

Including adenosylcobalamin, methylcobalamin, and hydroxocobalamin means you are getting broad-spectrum treatment in one convenient oil product. 

As a sublingual tincture, this product is held under the tongue as directed and allowed to absorb before being swallowed. 

Some also mix it into drinks to help it go down easier if they struggle with holding the liquid in their mouths. 

This product is also free of gluten, soy, dairy, GMOs, nuts, sugar, artificial flavors, synthetic dyes, and toxic fillers while being safe for all dietary types, including vegetarian, vegan, and pescetarian. 

With a simple ingredient list comprised of just B12 blend, organic vegetable glycerin, triple distilled water, and energized trace minerals, per their Amazon listing, this brand delivers a great taste and amazing benefits in one convenient, safe, and high-quality product.

Proper Supplementation

Supplementing your diet does not have to be expensive, difficult, or uncomfortable.

And adding the best form of Vitamin B12 into your diet isn’t difficult.  

There are tons of different products out there to help ensure you are getting all of the nutrients you need, no matter where you are or what you are eating. 

All of these products are easy to digest and made with your health in mind, making them great options for anyone looking to support their health while eating a vegan diet. 

It is just a matter of deciding which is right for you!